BDBM140387 US10947243, Example 112::US8912173, 112::US9914735, Example 112

SMILES C[C@@H](Oc1cc(cc2ncccc12)-c1cnn(C)c1C)[C@H]1CNC(=O)C1

InChI Key InChIKey=QUKCRTQLRUGASS-UKRRQHHQSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 140387   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140387(US10947243, Example 112 | US8912173, 112 | US99147...)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM140387(US10947243, Example 112 | US8912173, 112 | US99147...)
Affinity DataIC50:  6nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie—Dept. of Biochemistry) ...More data for this Ligand-Target Pair
In DepthDetails US Patent